160 research outputs found

    Journey Beyond Full Abstraction: Exploring Robust Property Preservation for Secure Compilation

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    —Good programming languages provide helpful abstractions for writing secure code, but the security properties of the source language are generally not preserved when compiling a program and linking it with adversarial code in a low-level target language (e.g., a library or a legacy application). Linked target code that is compromised or malicious may, for instance, read and write the compiled program’s data and code, jump to arbitrary memory locations, or smash the stack, blatantly violating any source-level abstraction. By contrast, a fully abstract compilation chain protects source-level abstractions all the way down, ensuring that linked adversarial target code cannot observe more about the compiled program than what some linked source code could about the source program. However, while research in this area has so far focused on preserving observational equivalence, as needed for achieving full abstraction, there is a much larger space of security properties one can choose to preserve against linked adversarial code. And the precise class of security properties one chooses crucially impacts not only the supported security goals and the strength of the attacker model, but also the kind of protections a secure compilation chain has to introduce. We are the first to thoroughly explore a large space of formal secure compilation criteria based on robust property preservation, i.e., the preservation of properties satisfied against arbitrary adversarial contexts. We study robustly preserving various classes of trace properties such as safety, of hyperproperties such as noninterference, and of relational hyperproperties such as trace equivalence. This leads to many new secure compilation criteria, some of which are easier to practically achieve and prove than full abstraction, and some of which provide strictly stronger security guarantees. For each of the studied criteria we propose an equivalent “property-free” characterization that clarifies which proof techniques apply. For relational properties and hyperproperties, which relate the behaviors of multiple programs, our formal definitions of the property classes themselves are novel. We order our criteria by their relative strength and show several collapses and separation results. Finally, we adapt existing proof techniques to show that even the strongest of our secure compilation criteria, the robust preservation of all relational hyperproperties, is achievable for a simple translation from a statically typed to a dynamically typed language

    Categorization of species as native or nonnative using DNA sequence signatures without a complete reference library.

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    New genetic diagnostic approaches have greatly aided efforts to document global biodiversity and improve biosecurity. This is especially true for organismal groups in which species diversity has been underestimated historically due to difficulties associated with sampling, the lack of clear morphological characteristics, and/or limited availability of taxonomic expertise. Among these methods, DNA sequence barcoding (also known as "DNA barcoding") and by extension, meta-barcoding for biological communities, has emerged as one of the most frequently utilized methods for DNA-based species identifications. Unfortunately, the use of DNA barcoding is limited by the availability of complete reference libraries (i.e., a collection of DNA sequences from morphologically identified species), and by the fact that the vast majority of species do not have sequences present in reference databases. Such conditions are critical especially in tropical locations that are simultaneously biodiversity rich and suffer from a lack of exploration and DNA characterization by trained taxonomic specialists. To facilitate efforts to document biodiversity in regions lacking complete reference libraries, we developed a novel statistical approach that categorizes unidentified species as being either likely native or likely nonnative based solely on measures of nucleotide diversity. We demonstrate the utility of this approach by categorizing a large sample of specimens of terrestrial insects and spiders (collected as part of the Moorea BioCode project) using a generalized linear mixed model (GLMM). Using a training data set of known endemic (n = 45) and known introduced species (n = 102), we then estimated the likely native/nonnative status for 4,663 specimens representing an estimated 1,288 species (412 identified species), including both those specimens that were either unidentified or whose endemic/introduced status was uncertain. Using this approach, we were able to increase the number of categorized specimens by a factor of 4.4 (from 794 to 3,497), and the number of categorized species by a factor of 4.8 from (147 to 707) at a rate much greater than chance (77.6% accuracy). The study identifies phylogenetic signatures of both native and nonnative species and suggests several practical applications for this approach including monitoring biodiversity and facilitating biosecurity

    Simulating the diversity of shapes of the Lyman-α\alpha line

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    The Lyα\alpha line is a powerful probe of distant galaxies, which contains information about inflowing/outflowing gas through which Lyα\alpha photons scatter. To develop our understanding of this probe, we post-process a zoom-in radiation-hydrodynamics simulation of a low-mass (M∗∌109M⊙M_* \sim 10^9 M_\odot) galaxy to construct 22500 mock spectra in 300 directions from z=3z = 3 to 4. Remarkably, we show that one galaxy can reproduce the variety of a large sample of spectroscopically observed Lyα\alpha line profiles. While most mock spectra exhibit double-peak profiles with a dominant red peak, their shapes cover a large parameter space in terms of peak velocities, peak separation and flux ratio. This diversity originates from radiative transfer effects at ISM and CGM scales, and depends on galaxy inclination and evolutionary phase. Red-dominated lines preferentially arise in face-on directions during post-starburst outflows and are bright. Conversely, accretion phases usually yield symmetric double peaks in the edge-on direction and are fainter. While resonant scattering effects at <0.2×Rvir< 0.2\times R_{\rm vir} are responsible for the broadening and velocity shift of the red peak, the extended CGM acts as a screen and impacts the observed peak separation. The ability of simulations to reproduce observed Lyα\alpha profiles and link their properties with galaxy physical parameters offers new perspectives to use Lyα\alpha to constrain the mechanisms that regulate galaxy formation and evolution. Notably, our study implies that deeper Lyα\alpha surveys may unveil a new population of blue-dominated lines tracing inflowing gas.Comment: Accepted for publication in MNRA

    Persistence, prevalence, and polymorphism of sequelae after COVID-19 in unvaccinated, young adults of the Swiss Armed Forces: a longitudinal, cohort study (LoCoMo)

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    Background: Persistent COVID-19 sequelae could have global, public health ramifications. We therefore aimed to describe sequelae presenting more than 180 days after COVID-19-focussing on several organ systems, general health, and laboratory parameters-in non-hospitalised, unvaccinated, young adults. Methods: We did a longitudinal cohort study of all army bases in Switzerland. Eligible participants were personnel of the Swiss Armed Forces (SAF) who were aged 18-30 years with a positive or negative RT-PCR test for SARS-CoV-2 during their service between March 1, 2020, and Dec 31, 2020. Exclusion criteria were unwillingness to participate in testing. Females or men with a known reproductive anomaly were excluded from the optional component of male fertility testing. COVID-19 was defined as a positive diagnostic RT-PCR test result for SARS-CoV-2 with concurrent symptoms compatible with COVID-19. Participants were subdivided into four groups: control group (ie, serologically negative), asymptomatic infection group (ie, serologically positive but with no symptoms), non-recent COVID-19 group (>180 days since positive PCR test), and recent COVID-19 group (≀180 days since positive PCR test). Outcomes of interest were part of a comprehensive, intensive test battery that was administered during a single day. The test battery quantified the effect of SARS-CoV-2 infection on cardiovascular, pulmonary, neurological, renal, ophthalmological, male reproductive, psychological, general health, and laboratory parameters. This study was registered with ClinicalTrials.gov, number NCT04942249. Findings: Between May 20, 2021, and Nov 26, 2021, we enrolled 501 participants. 29 (6%) of 501 were female and 464 (93%) were male, and the median age was 21 years (IQR 21-23). Eight (2%) of 501 had incomplete data and were not included into the study groups. 177 participants had previous COVID-19 that was more than 180 days (mean 340 days) since diagnosis (ie, the non-recent COVID-19 group) compared with 251 serologically negative individuals (ie, the control group). We included 19 participants in the recent COVID-19 group and 46 in the asymptomatic infection group. We found a significant trend towards metabolic disorders in participants of the non-recent COVID-19 group compared with those in the control group: higher BMI (median 24·0 kg/m2 [IQR 22·0-25·8] vs 23·2 kg/m2 [27·1-25·0]; p=0·035), lower aerobic threshold (39% [36-43] vs 41% [37-46]; p=0·012), and higher blood cholesterol (4·2 ÎŒM [3·7-4·7] vs 3·9 ÎŒM [3·5-4·5]; p<0·0001) and LDL concentrations (2·4 ÎŒM [1·9-2·9] vs 2·2 ÎŒM [1·7-2·7]; p=0·001). The only significant psychosocial difference was found in the results of the Chalder Fatigue scale with the non-recent COVID-19 group reporting higher fatigue scores than the control group (median 12 points [IQR 11-15] vs 11 [9-14]; p=0·027). No significant differences in other psychosocial questionnaire scores, ophthalmological outcomes, and sperm quality or motility were reported between the control group and non-recent COVID-19 group. Interpretation: Young, previously healthy, individuals largely recover from SARS-CoV-2 infection. However, the constellation of higher BMI, dyslipidaemia, and lower physical endurance 180 days after COVID-19 is suggestive of a higher risk of developing metabolic disorders and possible cardiovascular complications. These findings will guide future investigations and follow-up management

    The MUSE Hubble Ultra Deep Field Survey X. Lyα\alpha Equivalent Widths at 2.9<z<6.62.9 < z < 6.6

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    We present rest-frame Lyα\alpha equivalent widths (EW) of 417 Lyα\alpha emitters (LAEs) detected with Multi Unit Spectroscopic Explorer (MUSE) on the Very Large Telescope (VLT) at 2.9<z<6.62.9 < z < 6.6 in the Hubble Ultra Deep Field. Based on the deep MUSE spectroscopy and ancillary Hubble Space Telescope (HST) photometry data, we carefully measured EW values taking into account extended Lyα\alpha emission and UV continuum slopes (ÎČ\beta). Our LAEs reach unprecedented depths, both in Lyα\alpha luminosities and UV absolute magnitudes, from log(LLyαL_{\rm Ly\alpha}/erg s−1^{-1}) ∌\sim41.0 to 43.0 and from Muv ∌\sim -16 to -21 (0.01-1.0 Lz=3∗L^{*}_{\rm z=3}). The EW values span the range of ∌\sim 5 to 240 \AA\ or larger, and their distribution can be well fitted by an exponential law N=N0N = N_{\rm 0} exp(−-EW/w0w_{\rm 0}). Owing to the high dynamic range in Muv, we find that the scale factor, w0w_{\rm 0}, depends on Muv in the sense that including fainter Muv objects increases w0w_{\rm 0}, i.e., the Ando effect. The results indicate that selection functions affect the EW scale factor. Taking these effects into account, we find that our w0w_{\rm 0} values are consistent with those in the literature within 1σ1\sigma uncertainties at 2.9<z<6.62.9 < z < 6.6 at a given threshold of Muv and LLyαL_{\rm Ly\alpha}. Interestingly, we find 12 objects with EW >200>200 \AA\ above 1σ1\sigma uncertainties. Two of these 12 LAEs show signatures of merger or AGN activity: the weak CIV λ1549\lambda 1549 emission line. For the remaining 10 very large EW LAEs, we find that the EW values can be reproduced by young stellar ages (<100< 100 Myr) and low metallicities (â‰Č0.02\lesssim 0.02 Z⊙Z_{\rm \odot}). Otherwise, at least part of the Lyα\alpha emission in these LAEs needs to arise from anisotropic radiative transfer effects, fluorescence by hidden AGN or quasi-stellar object activity, or gravitational cooling.Comment: 22 pages, 12 figures, 9 tables, accepted for publication in A&A (MUSE UDF Series Paper X

    How to Quench a Dwarf Galaxy: The Impact of Inhomogeneous Reionization on Dwarf Galaxies and Cosmic Filaments

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    We use the SPHINX suite of high-resolution cosmological radiation hydrodynamics simulations to study how spatially and temporally inhomogeneous reionization impacts the baryonic content of dwarf galaxies and cosmic filaments. The SPHINX simulations simultaneously capture the large-scale process of reionization, model the escape of ionising radiation from thousands of galaxies, and resolve haloes well below the atomic cooling threshold. This makes them an ideal tool for examining how reionization impacts star formation and the gas content of dwarf galaxies. We compare simulations with and without stellar radiation to isolate the effects of radiation feedback from that of supernova, cosmic expansion, and numerical resolution. We find that the gas content of cosmic filaments can be reduced by more than 80% following reionization. The gas inflow rates into haloes with Mvirâ‰Č108M⊙M_{vir}\lesssim10^8M_{\odot} are strongly affected and are reduced by more than an order of magnitude compared to the simulation without reionization. A significant increase in gas outflow rates is found for halo masses Mvirâ‰Č7×107M⊙M_{vir}\lesssim7\times10^7M_{\odot}. Our simulations show that inflow suppression (i.e. starvation), rather than photoevaporation, is the dominant mechanism by which the baryonic content of high-redshift dwarf galaxies is regulated. At fixed redshift and halo mass, there is a large scatter in the halo baryon fractions that is entirely dictated by the timing of reionization in the local region surrounding a halo. Finally, although the gas content of high-redshift dwarf galaxies is significantly impacted by reionization, we find that most haloes with Mvirâ‰Č108M⊙M_{vir}\lesssim10^8M_{\odot} can remain self-shielded and form stars long after reionization, until their local gas reservoir is depleted, suggesting that local group dwarf galaxies do not necessarily exhibit star formation histories that peak prior to z=6z=6

    Predicting LyC emission of galaxies using their physical and Lyα\alpha emission properties

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    The primary difficulty in understanding the sources and processes that powered cosmic reionization is that it is not possible to directly probe the ionizing Lyman Continuum (LyC) radiation at that epoch as those photons have been absorbed by the intervening neutral hydrogen in the IGM on their way to us. It is therefore imperative to build a model to accurately predict LyC emission using other properties of galaxies in the reionization era. In recent years, studies have shown that the LyC emission from galaxies may be correlated to their Lya emission. Here, we study this correlation by analyzing thousands of galaxies at high-z in the SPHINX cosmological simulation. We post-process these galaxies with the Lya radiative transfer code RASCAS and analyze the Lya - LyC connection. We find that the Lya and LyC luminosities are strongly correlated with each other, although with dispersion. There is a positive correlation between Lya and LyC escape fractions in the brightest Lya emitters (>104110^{41} erg/s), similar to the recent observational studies. However, when we also include fainter Lya emitters (LAEs), the correlation disappears, which suggests that the observed relationship may be driven by selection effects. We also find that bright LAEs are dominant contributors to reionization (>1040> 10^{40} erg/s galaxies contribute >90%> 90\% of LyC emission). Finally, we build predictive models using multivariate linear regression where we use the physical and the Lya properties of simulated galaxies to predict their intrinsic and escaping LyC luminosities with a high degree of accuracy. We find that the most important galaxy properties to predict the escaping LyC luminosity of a galaxy are its escaping Lya luminosity, gas mass, gas metallicity, and SFR. These models can be very useful to predict LyC emissions from galaxies and can help us identify the sources of reionization.Comment: Accepted to Astronomy and Astrophysics (A&A) Journal. 27 pages, 21 Figure

    Interpreting the Si II and C II line spectra from the COS Legacy Spectroscopic SurveY using a virtual galaxy from a high-resolution radiation-hydrodynamic simulation

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    Observations of low-ionization state (LIS) metal lines provide crucial insights into the interstellar medium of galaxies, yet, disentangling the physical processes responsible for the emerging line profiles is difficult. This work investigates how mock spectra generated using a single galaxy in a radiation-hydrodynamical simulation can help us interpret observations of a real galaxy. We create 22,500 C II and Si II spectra from the virtual galaxy at different times and through multiple lines of sight and compare them with the 45 observations of low-redshift star-forming galaxies from the COS Legacy Spectroscopic SurveY (CLASSY). We find that the mock profiles provide accurate replicates to the observations of 38 galaxies with a broad range of stellar masses (10610^6 to 10910^9 M⊙M_\odot) and metallicities (0.02 to 0.55 Z⊙Z_\odot). Additionally, we highlight that aperture losses explain the weakness of the fluorescent emission in several CLASSY spectra and must be accounted for when comparing simulations to observations. Overall, we show that the evolution of a single simulated galaxy can produce a large diversity of spectra whose properties are representative of galaxies of comparable or smaller masses. Building upon these results, we explore the origin of the continuum, residual flux, and fluorescent emission in the simulation. We find that these different spectral features all emerge from distinct regions in the galaxy's ISM, and their characteristics can vary as a function of the viewing angle. While these outcomes challenge simplified interpretations of down-the-barrel spectra, our results indicate that high-resolution simulations provide an optimal framework to interpret these observations.Comment: Accepted for publication in Ap

    River ecosystem conceptual models and non‐perennial rivers: A critical review

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    Conceptual models underpin river ecosystem research. However, current models focus on continuously flowing rivers and few explicitly address characteristics such as flow cessation and drying. The applicability of existing conceptual models to nonperennial rivers that cease to flow (intermittent rivers and ephemeral streams, IRES) has not been evaluated. We reviewed 18 models, finding that they collectively describe main drivers of biogeochemical and ecological patterns and processes longitudinally (upstream-downstream), laterally (channel-riparian-floodplain), vertically (surface water-groundwater), and temporally across local and landscape scales. However, perennial rivers are longitudinally continuous while IRES are longitudinally discontinuous. Whereas perennial rivers have bidirectional lateral connections between aquatic and terrestrial ecosystems, in IRES, this connection is unidirectional for much of the time, from terrestrial-to-aquatic only. Vertical connectivity between surface and subsurface water occurs bidirectionally and is temporally consistent in perennial rivers. However, in IRES, this exchange is temporally variable, and can become unidirectional during drying or rewetting phases. Finally, drying adds another dimension of flow variation to be considered across temporal and spatial scales in IRES, much as flooding is considered as a temporally and spatially dynamic process in perennial rivers. Here, we focus on ways in which existing models could be modified to accommodate drying as a fundamental process that can alter these patterns and processes across spatial and temporal dimensions in streams. This perspective is needed to support river science and management in our era of rapid global change, including increasing duration, frequency, and occurrence of drying.info:eu-repo/semantics/publishedVersio
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